還元端にN−アセチルグルコサミン残基を添加するためには,グリコシル化反応が必要である。これは、保護されたヒアルロン酸断片を保護されたN-アセチルグルコサミン誘導体に結合させることを含む。通常DCC(ジシクロヘキシルカルボジイミド)やHOBt(1−ヒドロキシベンゾトリアゾール)などの活性化剤が用いられる。反応は地域選択性を確実にするために慎重に監視されなければならない。
化学原料を購入する必要がある場合は、 要求情報を送信してください最新の見積りを入手してください。
4-methoxyphenyl O-(β-D-glucopyranosyluronic acid)-(1->3)-O-(2-acetamido-2-deoxy-β-D-glucopyranosyl)-(1->4)-O-(β-D-glucopyranosyluronic acid)-(1->3)-2-acetamido-2-deoxy-β-D-glucopyranoside
C16H18O3
C55H46O12
Chloro-acetic acid (2R,3R,4S,5R,6R)-4-benzyloxy-5-hydroxy-6-hydroxymethyl-2-(2-trimethylsilanyl-ethoxy)-tetrahydro-pyran-3-yl ester
Acetic acid (2S,3R,4R,5R,6S)-3-acetoxy-6-{(2S,3R,4S,6S)-4-benzyloxy-6-[(2S,3S,4S,6R)-6-benzyloxy-2-methyl-4-(2,2,2-trifluoro-acetylamino)-tetrahydro-pyran-3-yloxy]-2-methyl-tetrahydro-pyran-3-yloxy}-5-iodo-2-methyl-tetrahydro-pyran-4-yl ester
dimethylthexylsilyl O-(methyl 2-O-levulinoyl-3-O-benzyl-4-O-(9-O-fluorenylmethoxycarbonyl)-β-D-glucopyranosyluronate)-(1->4)-O-2-azido-3-O-benzyl-2-deoxy-6-O-acetyl-β-D-glucopyranoside
D-ガラクタール
D-グルカール
NaH
ジクロロメタン(別名塩化メチレン)
18-クラウン-6
アジ化ナトリウム
4-METHOXY-1H-PYRAZOLO[3,4-D]PYRIMIDIN-6-AMINE
Nγ-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl)-Nα-(fluoren-9-ylmethoxycarbonyl)-L-asparagine pentafluorophenyl ester
フェンチドロン
ピリジン
propargyl 3-O-benzoyl-4,6-O-benzylidene-β-D-glucopyranoside
トリエチルアミン
phenyl 2,3-di-O-benzyl-4-O,6-S-benzylidene-1,6-dithio-α-D-mannopyranoside
water
methyl 6-deoxy-α/β-D-galactopyranoside
5,4'-di-O-hexanoylgenistein-7-yl 2'',3'',4'',6''-tetra-O-acetyl-β-D-glucopyranoside
2,3,4,6-TETRA-O-BENZOYL-ALPHA-D-GLUCOPYRANOSYL P-TRIFLUOROMETHYLBENZYLTHIO-N-(P-TRIFLUOROMETHYLPHENYL)FORMIMIDATE
3,4,6-Tri-O-acetyl-α-D-galactopyranose 1,2-(endo-methyl orthoacetate)
(2-acetamido-4,6-di-O-acetyl-2-deoxy-3-O-methyl-α-D-galactopyranosyl)-(1<*>3)-4)>-1-O-acetyl-2-O-benzyl-L-fucopyranose
1,3,4,6-tetra-O-acetyl-2-O-benzoyl-α-D-galactopyranose
ペリロシドA
4-nitrophenyl O-α-L-fucopyranosyl-(1->3)-O-(2-acetamido-2-deoxy-β-D-glucopyranosyl)-(1->3)-O-β-D-galactopyranosyl-(1->3)-2-acetamido-2-deoxy-β-D-glucopyranoside
4-Methoxy-benzoic acid (2R,3R,4S,5R,6R)-2-((2R,3S,4S,5R,6S)-5-benzoyloxy-3-benzyloxy-4-hydroxy-6-phenylsulfanyl-tetrahydro-pyran-2-ylmethoxy)-4,5-bis-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-3-yl ester
phenyl (2-O-acetyl-3,4,6,-tri-O-benzyl-α-D-mannopyranosyl-(1->3)-2,4,6-tri-O-acetyl-1-thio-α-D-mannopyranoside)
methyl 2,3,4-tri-O-benzyl-6-O--β-D-erythro-L-gluco-2-nonulopyranosyl)onate>-α-D-glucopyranoside
トリエチルシラン
acetonitrile
C54H46N2O17S
O5'-(2-hexopyranosyloxy-1,2-dihydroxy-diphosphoryl)-guanosine
O-[3-O,4-O,6-O-トリアセチル-2-(アセチルアミノ)-2-デオキシ-β-D-グルコピラノシル]-N-[(フェニルメトキシ)カルボニル]-L-セリンメチル
ethyl 6-O-tert-butyldiphenylsilyl-2-deoxy-2-phthalimido-1-thio-β-glucopyranoside
1,3,6-tri-O-acetyl-4-O-benzyl-2-O-[(R)-α-(ethoxycarbonyl)benzyl]-α-D-glucopyranose
t-butyldimethylsilyl 3-O-allyloxycarbonyl-4,6-O-benzylidene-2-O-{(1S)-phenyl-2-phenylsulfanyl-ethyl}-β-D-glucopyranoside
N-benzyloxycarbonyl-O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1->3)-O-(2,4,6-tri-O-acetyl-β-D-galactopyranosyl)-(1->4)-O-(2,3-di-O-acetyl-β-D-xylopyranosyl)-(1->3)-L-serine benzyl ester
methyl 2,3,4-tri-O-benzyl-6-O-2-(2-nitrophenyl)propyloxycarbonyl-α-D-glucopyranoside