体外検査
合成した化合物は体外実験で培養細胞を用いて試験を行った。細胞に基づく分析は、これらの化合物が腫瘍壊死因子-αの産生を抑制し、あるいは炎症反応を調節する能力を測定することができる。
化学原料を購入する必要がある場合は、 要求情報を送信してください最新の見積りを入手してください。
体外検査の学術論文
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Synthesis and biological evaluation of new pyrazolone-pyridazine conjugates as anti-inflammatory and analgesic agents
関連化学物質
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3-[2-(6-chloropyridazin-3-ylamino)phenylamino]-1H-pyrazol-5(4H)-one
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Synthesis and anti-candida potential of certain novel 1-[(3-substituted-3- phenyl)propyl]-1H-imidazoles
関連化学物質
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3-(1H-imidazol-1-yl)-1-phenylpropyl benzoate
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SYNTHESIS AND STUDY OF THE ANTIVIRAL ACTIVITY OF PROPANOLAMINE DERIVATIVES
関連化学物質
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Benzamide, N-(2-hydroxy-3-phenoxypropyl)-4-nitro-
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Preparation and anti-inflammatory activities of diarylheptanoid and diarylheptylamine analogs
関連化学物質
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3-Heptanone, 1,7-bis(4-hydroxy-3-methoxyphenyl)-
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Synthesis and elastase-inhibiting activity of 2-pyridinyl-isothiazol-3(2H)-one 1,1-dioxides
関連化学物質
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2-(6-chloropyridin-2-yl)-4,5,6,7-tetrahydro-1,2-benzoisothiazolium perchlorate
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Design, synthesis, and antitumor activities of some novel substituted 1,2,3-benzotriazines
関連化学物質
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2-amino-4-ethoxy-5-methoxybenzonitrile
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Identification of arginine analogues as antagonists and agonists for the melanocortin-4 receptor
関連化学物質
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(S)-2-TERT-BUTOXYCARBONYLAMINO-3-NAPHTHALEN-2-YL-PROPIONIC ACID METHYL ESTER
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Optimization of novel indole-2-carboxamide inhibitors of neurotropic alphavirus replication
関連化学物質
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methyl 1-(4-chlorobenzyl)-1H-pyrrole-2-carboxylate
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Synthesis and evaluation of 2′,4′,6′-trihydroxychalcones as a new class of tyrosinase inhibitors
関連化学物質
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4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-
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Synthesis of new N-isobutyryl-l-cysteine/MEA conjugates: Evaluation of their free radical-scavenging activities and anti-HIV properties in human macrophages
関連化学物質
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Ethanethioic acid, S-[2-[[(2R)-2-(acetylamino)-1-oxo-3-[(triphenylmethyl)thio]propyl]amino] ethyl] ester
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Synthesis, anti-inflammatory evaluation and docking studies of some new fluorinated fused quinazolines
関連化学物質
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5-(furan-2-yl)-8-phenyl-10-(trifluoromethyl)-2,3-dihydroimidazo[1,2-c]quinazoline-7-carboxamide
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2,6-Disubstituted imidazo[2,1-b][1,3,4]thiadiazoles: Search for anticancer agents
関連化学物質
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2-(2-fluorobiphenyl-4-yl)-6-phenylimidazo[2,1-b][1,3,4]thiadiazole
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Isoxazolopyrimidines as novel F508-CFTR correctors
関連化学物質
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4-isoxazolecarboxamide, 5-amino-3-(3-chlorophenyl)-
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Synthesis and α-glucosidase-inhibiting activity of a new α-glucosidase inhibitor, 4-O-α-D-glucopyranosylmoranoline and its N-substituted derivatives
関連化学物質
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(2S,3R,4S,5S,6R)-2-[(2R,3R,4R,5S)-4,5-Dihydroxy-2-hydroxymethyl-1-(4-methyl-benzyl)-piperidin-3-yloxy]-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol
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Further explorations on bridged 1,2,4-trioxanes
関連化学物質
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5-[5-(tert-butyl-dimethyl-silanyloxy)-pentane-1-sulfonyl]-1-phenyl-1H-tetrazole
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Resolved 3-(3-Hydroxyphenyl)-N-n-propylpiperidine and Its Analogues: Central Dopamine Receptor Activity
関連化学物質
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(+)-3-PPP hydrobromide
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Discovery of 8-Amino-imidazo[1,5-a]pyrazines as Reversible BTK Inhibitors for the Treatment of Rheumatoid Arthritis
関連化学物質
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4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-N-(4-trifluoromethyl-pyridin-2-yl)benzamide
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Synthesis, anticandidal activity and cytotoxicity of some tetrazole derivatives
関連化学物質
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1-(4-fluorophenyl)-2-[(1-methyl-1H-tetraazol-5-yl)sulfanyl]ethanone
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Design, synthesis, and biological evaluation of a series of 2-hydroxyisoquinoline-1,3(2H,4H)-diones as dual inhibitors of human immunodeficiency virus type 1 integrase and the reverse transcriptase RNase H domain
関連化学物質
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2-(carboxymethyl)-5-{[(3-nitrophenyl)carbonyl]amino}benzoic acid
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Synthesis of 2-amino-3-arylpropan-1-ols and 1-(2,3-diaminopropyl)-1,2,3- triazoles and evaluation of their antimalarial activity
関連化学物質
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2-(N-isobutylamino)-3-(4-methoxyphenyl)propan-1-ol
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Synthesis of novel N-branched acyclic nucleoside phosphonates as potent and selective inhibitors of human, plasmodium falciparum and plasmodium vivax 6-oxopurine phosphoribosyltransferases
関連化学物質
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シリカゲル
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diethyl 2-((2-hydroxyethyl)(2-(trityloxy)ethyl)amino)ethylphosphonate
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Molecular design, synthesis and biological evaluation of BP-O-DAPY and O-DAPY derivatives as non-nucleoside HIV-1 reverse transcriptase inhibitors
関連化学物質
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エチレンジアミンテトラ酢酸
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Picogreen
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4-{4-[2-benzoyl-5-methoxyphenoxy]pyrimidin-2-ylamino}benzonitrile
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Synthesis and antibacterial evaluation of tetrahydropyrimidine-5-carboxamide
関連化学物質
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6-methyl-N-phenyl-4-thien-2-yl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide
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Design and synthesis of new 7-(N-substituted-methyl)-camptothecin derivatives as potent cytotoxic agents
関連化学物質
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7-(N-(2-methoxyphenylamino)methyl)-(20S)-camptothecin
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Synthesis and evaluation of 5′-modified 2′-deoxyadenosine analogues as anti-hepatitis C virus agents
関連化学物質
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3-[(2R,3S,5R)-5-(6-chloro-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl]-1-phenylpropan-1-one
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Synthesis and structural analysis of halogen substituted fibril formation inhibitors of Human Transthyretin (TTR)
関連化学物質
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Methanone, (3,4-dichlorophenyl)phenyl-, oxime
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Functional divergence between closely related Baeyer-Villiger monooxygenases from Aspergillus flavus
関連化学物質
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α-methyl-δ-valerolactone
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Potent and selective non-benzodioxole-containing endothelin-A receptor antagonists
関連化学物質
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4-(2,4-Dimethoxy-phenyl)-2-(4-methoxy-phenyl)-4,5-dihydro-3H-pyrrole-3-carboxylic acid ethyl ester
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Phenotypic Optimization of Urea-Thiophene Carboxamides to Yield Potent, Well Tolerated, and Orally Active Protective Agents against Aminoglycoside-Induced Hearing Loss
関連化学物質
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tert-butyl 3-carbamoyl-2-[3-(4-chlorophenyl)ureido]-4,5-dihydrothieno[2,3-c]pyridine-6(7H)-carboxylate
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8-Substituted 3,4-dihydroquinolinones as a novel scaffold for atypical antipsychotic activity
関連化学物質
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Benzoylcholine Chloride
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Discovery of novel urea-based hepatitis C protease inhibitors with high potency against protease-inhibitor-resistant mutants
関連化学物質
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N-(6-acetyl-3-methoxy-2-methylphenyl)-4-cyclopropylthiazole-2-carboxamide
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A novel series of 6-methoxy-1H-benzotriazole-5-carboxamide derivatives with dual antiemetic and gastroprokinetic activities
関連化学物質
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Benzoic acid, 4-(acetylamino)-5-chloro-2-methoxy-3-nitro-, methyl ester
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Design synthesis and antibacterial activity studies of new thiadiazoloquinolone compounds
関連化学物質
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ethyl 2-[(2,4-dichloro-5-fluoro-3-nitrophenyl)carbonyl]-3-(dimethylamino)prop-2-enoate
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Pyrimidine-2,4-diamines as antiplasmodial antifolates
関連化学物質
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2,4-dibromo-1-(4-bromobutoxy)Benzene
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Fluorine-substituted dihydrobicyclomycins: Synthesis and biochemical and biological properties
関連化学物質
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Ethanethioic acid, S-[[3,5-bis(trifluoromethyl)phenyl]methyl] ester
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8-Azapurines as new inhibitors of cyclin-dependent kinases
関連化学物質
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9-benzyl-2,6-dihydroxy-8-azapurine
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