薬物化学
薬物化学研究薬物の設計·開発と合成の化学分野
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薬物化学の学術論文
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Synthesis of 4-alkyl-, 4-aryl- and 4-arylamino-5-aminoisoquinolin-1-ones and identification of a new PARP-2 selective inhibitor
関連化学物質
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1-methoxy-5-nitro-4-phenylisoquinoline
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Synthesis of 1,1-difluoroethylsilanes and their application for the introduction of the 1,1-difluoroethyl group
関連化学物質
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(1,1-difluoroethyl)triethylsilane
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Identification of a potent and selective free fatty acid receptor 1 (FFA1/GPR40) agonist with favorable physicochemical and in vitro ADME properties
関連化学物質
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methyl 3-(4-((2-chloropyridin-4-yl)ethynyl)phenyl)propanoate
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Lead optimization of isocytosine-derived xanthine oxidase inhibitors
関連化学物質
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C16H18N4O2
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Optimization of novel indole-2-carboxamide inhibitors of neurotropic alphavirus replication
関連化学物質
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methyl 1-(4-chlorobenzyl)-1H-pyrrole-2-carboxylate
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Dibenzylideneacetone analogues as novel Plasmodium falciparum inhibitors
関連化学物質
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C23H18F2N2
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Rational discovery of a highly novel and selective mTOR inhibitor
関連化学物質
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1-cyclopropyl-3-(4-(5-(2,2-difluoropropyl)-6a-methyl-6-oxo-5,6,6a,7,9,10-hexahydro[1,4]oxazino[3,4-h]pteridin-2-yl)phenyl)urea
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Development of Kinase Inactive PD173955 Analogues for Reducing Production of Aβ Peptides
関連化学物質
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6-(2,6-DICHLOROPHENYL)-8-METHYL-2-METHYLSULFONYL-8H-PYRIDO[2,3-D]PYRIMIDIN-7-ONE
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Synthesis of selective inhibitors against V. cholerae sialidase and human cytosolic sialidase NEU2
関連化学物質
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methyl acetamido-2,6-anhydro-3,5-dideoxy-9-p-toluenesulfonyl-D-glycero-D-galactonon-2-enonate
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Structure-based optimization of pyrazolo-pyrimidine and -pyridine inhibitors of PI3-kinase
関連化学物質
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4,6-DICHLORO-1-METHYL- 1H-PYRAZOLO[3,4-B]PYRIDINE
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尿素?塩酸塩
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Diversity-oriented synthesis-facilitated medicinal chemistry: Toward the development of novel antimalarial agents
関連化学物質
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4-fluoro-N-(((7R,8R,14S)-5-((2S)-1-((4-methoxybenzyl)oxy)propan-2-yl)-1,7,14-trimethyl-4-oxo-4,5,6,7,8,10,11,12,13,14-decahydro-1H-pyrazolo[3,4-b][1,9,5]dioxaazacyclotetradecin-8-yl)methyl)-N-methylbenzenesulfonamide
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A novel route to synthesize libraries of quinoxalines via Petasis methodology in two synthetic operations
関連化学物質
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2-(2-methoxyphenyl)-3-phenylquinoxaline
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Analogues of thiolactomycin as potential anti-malarial and anti-trypanosomal agents
関連化学物質
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Pentanoic acid, 2-ethyl-3-oxo-, methyl ester
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The discovery and optimization of benzimidazoles as selective NaV1.8 blockers for the treatment of pain
関連化学物質
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N-(4-(2-cyanopropan-2-yl)-2-nitrophenyl)acetamide
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Catalytic asymmetric hydrogenation of N-Boc-imidazoles and oxazoles
関連化学物質
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4-ETHYL-2-PHENYL-1H-IMIDAZOLE
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A convenient synthesis of N-benzylpiperazine, 1-aralkyl-4-benzylpiperazines and an Isostere of Idebenone
関連化学物質
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2-chloromethyl-3,4,5-trimethoxytoluene
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8-Substituted 3,4-dihydroquinolinones as a novel scaffold for atypical antipsychotic activity
関連化学物質
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Benzoylcholine Chloride
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Quantitative Structure-Activity Relationships of Colchicines against P388 Leukemia in Mice
関連化学物質
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N-[(7S)-1,2,3-trimethoxy-10-(methylsulfonyl)-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide
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Oxindole derivatives as orally active potent growth hormone secretagogues
関連化学物質
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3-(2-chlorophenyl)-1-(2-diethylaminoethyl)-3-hydroxy-6-iodo-4-trifluoromethyloxindole
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Design and synthesis of C-linked fucosides as inhibitors of E-selectin
関連化学物質
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2-(4:6-p-methoxybenzylidene-2:3-carbonylmethylene-β-D-galactopyranosyl)acetaldehyde
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Pyrazolo[1,5-a]pyridines as p38 kinase inhibitors
関連化学物質
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3-Pyridinecarbonitrile, 6-[2-(4-fluorophenyl)-2-oxoethyl]-
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Discovery of imidazopyridazines as potent Pim-1/2 kinase inhibitors
関連化学物質
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(S)-tert-butyl 1-(3-aminopyridin-4-yl)piperidin-3-ylcarbamate
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