動物研究
次に動物モデルにおいて有望な化合物を評価し，体内での有効性と安全性を評価した。このステップは，これらの化合物の抗癌薬としてのさらなる開発の潜在力を決定するために重要である。
化学原料を購入する必要がある場合は、 要求情報を送信してください最新の見積りを入手してください。
動物研究の学術論文
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Structure-based design, synthesis and biological testing of etoposide analog epipodophyllotoxin-N-mustard hybrid compounds designed to covalently bind to topoisomerase II and DNA
関連化学物質
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4β-chloroacetamido-4-deoxy-4′-desmethylepipdophyllotoxin
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Design, synthesis, and biological evaluation of N-acetyl-2-(or 3-)carboxymethylbenzenesulfonamides as cyclooxygenase isozyme inhibitors
関連化学物質
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4-fluoro-2-(methoxycarbonylmethyl)benzenesulfonamide
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Synthesis and biological evaluation of the pyrazole class of cyclooxygenase-2-inhibitors
関連化学物質
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3-(4-chlorophenyl)-1-(4-nitrophenyl)-1H-pyrazole-4-carbaldehyde
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Identification of a novel fluoropyrrole derivative as a potassium-competitive acid blocker with long duration of action
関連化学物質
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1-[5-(2-Fluoropyridin-3-yl)-1-(phenylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine fumarate
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Preparation and anti-inflammatory activities of diarylheptanoid and diarylheptylamine analogs
関連化学物質
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3-Heptanone, 1,7-bis(4-hydroxy-3-methoxyphenyl)-
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Synthesis of new substance P analogues releasing histamine from rat peritoneal mast cells
関連化学物質
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Boc-Pro-Lys(Z)-Pro-OCH3
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)
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Synthesis and elastase-inhibiting activity of 2-pyridinyl-isothiazol-3(2H)-one 1,1-dioxides
関連化学物質
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2-(6-chloropyridin-2-yl)-4,5,6,7-tetrahydro-1,2-benzoisothiazolium perchlorate
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Synthesis of arylidene-substituted gelastatin analogues and their screening for MMP-2 inhibitory activity
関連化学物質
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トリエチルアミン
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methyl acrylate
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9-BBN
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Synthesis and evaluation of novel benzimidazole derivatives as antimicrobial agents
関連化学物質
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N-(4-chloro-3-fluorophenyl)-2-(5-methoxy-1H-benzo[d]imidazol-2-ylthio)acetamide
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Metallocene-based inhibitors of cancer-associated carbonic anhydrase enzymes IX and XII
関連化学物質
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4-(ジメチルアミノ)ピリジン
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AMINES
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4-(5-phenyl-1H-1,2,3-triazol-1-yl)benzenesulfonamide
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Development of new LXR modulators that regulate LXR target genes and reduce lipogenesis in human cell models
関連化学物質
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12
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4-(bromomethyl)-N-cyclohexyl-N-methylbenzenesulfonamide
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Design, synthesis, and biological evaluation of alcyopterosin a and illudalane derivatives as anticancer agents
関連化学物質
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4-BroMo-5,7-diMethyl-2,3-dihydro-1H-inden-1-one
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Parallel synthesis of DAPT derivatives and their γ-secretase- inhibitory activity
関連化学物質
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Glycine, N-[(3,5-difluorophenyl)acetyl]-L-alanyl-2-phenyl-, (2S)-
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Design, synthesis, and biological evaluation of novel piperidine-4- carboxamide derivatives as potent CCR5 inhibitors
関連化学物質
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tert-butyl 4-(4-cyanobenzylcarbamoyl)piperidine-1-carboxylate
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Rational discovery of a highly novel and selective mTOR inhibitor
関連化学物質
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1-cyclopropyl-3-(4-(5-(2,2-difluoropropyl)-6a-methyl-6-oxo-5,6,6a,7,9,10-hexahydro[1,4]oxazino[3,4-h]pteridin-2-yl)phenyl)urea
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Synthesis and cytotoxicity studies of novel [1,2,4] Triazolo [1,5-a]pyrimidine-7-amines
関連化学物質
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N-(3-chlorophenyl)-5-methyl-2-(3-((5-(morpholinomethyl)furan-2-yl)methylthio)propyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
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TVB-2640
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Synthesis of novel N-branched acyclic nucleoside phosphonates as potent and selective inhibitors of human, plasmodium falciparum and plasmodium vivax 6-oxopurine phosphoribosyltransferases
関連化学物質
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シリカゲル
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diethyl 2-((2-hydroxyethyl)(2-(trityloxy)ethyl)amino)ethylphosphonate
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Design, synthesis, and evaluation of imidazo[1,2-b]pyridazine derivatives having a benzamide unit as novel VEGFR2 kinase inhibitors
関連化学物質
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N-[4-(imidazo[1,2-b]pyridazin-6-yloxy)phenyl]-N'-phenylurea
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5-(ω-aminoalkyl)aminoisoxazoles with hypertensive activity: Synthesis and screening of compounds with a sulfamide or carboxyl function at the end of the side chain
関連化学物質
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N-Phenyl-N-<3-(4-chlorphenyl)-4-phenylisoxazol-5-yl>-aminoessigsaeure
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Design and synthesis of nonsteroidal progesterone receptor antagonists based on C,C′-diphenylcarborane scaffold as
ahydrophobic pharmacophore関連化学物質
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1-(4-cyanophenyl)-2-(4-nitrophenyl)-1,2-dicarba-closo-dodecaborane
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Carbon-14 labeling of a potential new immunoregulant agent
関連化学物質
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4-(3',5'-dimethoxyphenyl)-1-(1-tetrahydrofuranyl)imidazole
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Design, synthesis and evaluation of marinopyrrole derivatives as selective inhibitors of Mcl-1 binding to pro-apoptotic Bim and dual Mcl-1/Bcl-xL inhibitors
関連化学物質
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テトラヒドロフラン
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ジクロロメタン（別名塩化メチレン）
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acetonitrile
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Benzimidazole-derived ATP analogues as potential glutamine synthetase inhibitors
関連化学物質
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1-アリル-1H-ベンゾイミダゾール
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